NEXT-GENERATION CARDIOVASCULAR DEVICES

Preserving the lumen after cardiovascular intervention.

Mission: MAXLumen® is developing a locally delivered therapy designed to address the inflammation and pathological cardiovascular remodeling that leads to restenosis following angioplasty.

Artery narrowed by plaque buildup

Occluded Artery

Narrowed artery caused by plaque buildup.

Balloon angioplasty opening the artery

Balloon Angioplasty

Balloon insertion and expansion to open the artery.

Blood flow restored following angioplasty

Blood Flow Restored

Angioplasty reopens the narrowed artery and restores blood flow.

Vascular inflammation and tissue remodeling

Vascular Response

The treated vessel responds through inflammation and tissue remodeling.

Artery narrowed again through restenosis

Restenosis

Excessive healing can narrow the lumen again and compromise the benefit of the procedure.

Artery narrowed by plaque buildup

Occluded Artery

Narrowed artery caused by plaque buildup.

Balloon angioplasty opening the artery

Balloon Angioplasty

Balloon insertion and expansion to open the artery.

Blood flow restored following angioplasty

Blood Flow Restored

Angioplasty reopens the narrowed artery and restores blood flow.

Vascular inflammation and tissue remodeling

Vascular Response

The treated vessel responds through inflammation and tissue remodeling.

Artery narrowed again through restenosis

Restenosis

Excessive healing can narrow the lumen again and compromise the benefit of the procedure.

THE CHALLENGE

Opening the artery is only the first step.

OUR APPROACH

Using a novel anti-inflammatory & anti-fibrotic oxysterol-coated balloon.

MAXLumen is developing a locally delivered therapy designed to act directly at the treatment site, when the artery is already being accessed during angioplasty.

Localized oxysterol delivery to the vessel wall

Deliver

The therapeutic agent is transferred locally to the vessel wall during balloon angioplasty.

Reduced inflammation and fibrosis within the treated vessel

Calm

Early therapeutic action is designed to reduce inflammation and abnormal vascular remodeling following the procedure.

Healthier open vessel with restored blood flow

Control

Sustained anti-proliferative action is designed to limit excessive tissue growth and help preserve the restored lumen.